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Friday, October 23, 2026 · Today’s edition, 6:30 a.m. ETFri, Oct 23 · 6:30 a.m. editionSign inMy Desk 0EditionsSign in
SBIOALPS FundsACTIVE

ALPS Medical Breakthroughs ETF

$54.55-0.04% vs prior close
427152-WK

Price through Oct 22, 2026 · Flows through unavailable. Figures use the latest available records, not a live quote. Fund details retrieved Oct 22, 2026. Holdings snapshot retrieved Oct 22, 2026.

The fund employs a "passive management" - or indexing - investment approach designed to track the performance of the underlying index. It will normally invest at least 80% of its net assets in securities that comprise the underlying index. The underlying index is comprised of small and mid-cap stocks of biotechnology companies that have one or more drugs in either Phase II or Phase III of the U.S. Food and Drug Administration clinical trials.

SBIO price

Source: Market tape, daily closes; price return, distributions not reinvested
Table
DateSBIO close
Sep 22, 2026$63.35
Sep 23, 2026$59.85
Sep 24, 2026$58.55
Sep 25, 2026$57.56
Sep 28, 2026$57.93
Sep 29, 2026$57.94
Sep 30, 2026$58.30
Oct 1, 2026$56.64
Oct 2, 2026$56.15
Oct 5, 2026$56.26
Oct 6, 2026$54.38
Oct 7, 2026$54.13
Oct 8, 2026$53.95
Oct 9, 2026$55.04
Oct 12, 2026$53.85
Oct 13, 2026$51.64
Oct 14, 2026$51.20
Oct 15, 2026$52.22
Oct 16, 2026$50.12
Oct 19, 2026$52.11
Oct 20, 2026$54.81
Oct 21, 2026$54.57
Oct 22, 2026$54.55

The desk’s read

Recent fund-flow records are unavailable, while the price has returned +6.5% so far this year. At 0.50% a year it is not the cheapest way in — IWM has a reported fee of 0.19%.

COMPOSED FROM THE FUND’S OWN DAILY RECORDS · UPDATED WITH EACH REFRESH

$114Massets under management
0.50%expense ratio · $50 per $10,000 a year
—net flow, trailing month
41Kavg daily volume, 30 days
95holdings · US-domiciled
2014listed December 30, 2014 · beta 1.04

Sector weights

  • Healthcare100%
  • Health Technology97.84%
  • Other4.16%
  • Health Services2.19%
  • Mutual fund0.07%
Source: Portfolio composition, latest disclosure
Show as table
ItemValue (%)
Healthcare100%
Health Technology97.84%
Other4.16%
Health Services2.19%
Mutual fund0.07%

Country weights

  • United States84.79%
  • Netherlands4.21%
  • United Kingdom3%
  • Switzerland2.26%
  • Canada2.18%
  • France1.54%
  • China1.21%
  • Belgium1.19%
Source: Portfolio composition, latest disclosure
Show as table
ItemValue (%)
United States84.79%
Netherlands4.21%
United Kingdom3%
Switzerland2.26%
Canada2.18%
France1.54%
China1.21%
Belgium1.19%
Performance
1 week+8.8%
1 month-13.9%
3 months-14.9%
6 months-3.9%
YTD+6.5%
1 year+29.8%
3 years—

PRICE RETURN, DISTRIBUTIONS NOT REINVESTED

Net flows
1 week—
1 month—
3 months—
YTD—
1 year—

CREATION/REDEMPTION DOLLARS, DAILY RECORDS

The risk read
41%realized volatility, 30 days (annualized)
32%realized volatility, 1 year
-29.2%deepest fall from a peak, 1 year
-22.9%latest close versus that peak

VOLATILITY & DRAWDOWN FROM THE DAILY TAPE · CONCENTRATION FROM THE LATEST DISCLOSED BOOK

Options tape
—calls · latest snapshot
—puts · latest snapshot
—put/call ratio
13Kshares traded
The case against SBIO

Due diligence cuts both ways. These funds sit on the same shelf and beat SBIO on at least one dimension that matters — the fee, the asset base, or where the money is going.

FundFeeAssetsFlow, 1MThe case
SPDW SPDR Portfolio Developed World ex-US ETF0.03%$41.2B+$609M-47bp on fee · 361× the assets · +$609M in over the monthHead-to-head
SPMD State Street SPDR Portfolio S&P 400 Mid Cap ETF0.03%$18.4B+$199M-47bp on fee · 161× the assets · +$199M in over the monthHead-to-head
IDEV iShares Core MSCI International Developed Markets ETF0.04%$32.4B+$497M-46bp on fee · 284× the assets · +$497M in over the monthHead-to-head
IGIB iShares 5-10 Year Investment Grade Corporate Bond ETF0.04%$18.6B+$412M-46bp on fee · 163× the assets · +$412M in over the monthHead-to-head
IEFA iShares Core MSCI EAFE ETF0.07%$191B+$817M-43bp on fee · 1674× the assets · +$817M in over the monthHead-to-head
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