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Friday, October 2, 2026The Morning Brief →Sign in
PBEInvescoACTIVE

Invesco Dynamic Biotechnology & Genome ETF

$95.10-2.25% vs prior close
709952-WK

Price through Oct 1 · Flows through Sep 30. Figures use the latest available records, not a live quote. Fund details retrieved Oct 1. Holdings snapshot retrieved Oct 1.

The fund generally will invest at least 90% of its total assets in the securities that comprise the underlying intellidex. The underlying intellidex was composed of common stocks of U.S. biotechnology and genome companies. These companies are engaged principally in the research, development, manufacture and marketing and distribution of various biotechnological products, services and processes, etc. It is non-diversified.

Price & daily flows
92.684.576.595.10DAILY NET FLOWOct 1Jan 30Jun 1Oct 1

SOURCE: MARKET TAPE & DAILY CREATION/REDEMPTION RECORDS · 1Y SHOWN · NET +$114M OVER THIS RANGE

The desk’s read

Money is leaving — −$50M in net outflows over the past month, about 11.8% of the fund's asset base, while the price has returned +15.8% so far this year. At 0.58% a year it is not the cheapest way in — FDHT has a reported fee of 0.39%.

COMPOSED FROM THE FUND’S OWN DAILY RECORDS · UPDATED WITH EACH REFRESH

$424Massets under management
0.58%expense ratio · $58 per $10,000 a year
−$50Mnet flow, trailing month
18Kavg daily volume, 30 days
31holdings · US-domiciled
2005listed June 23, 2005 · beta 0.64
The book at a glance
NTRA-1.2%ILMN-2.9%BIIB-1.4%GILD-1.0%RPRX-1.3%AMGN-3.4%VRTX-3.1%REGN-3.1%MRNA-1.9%NVAX-1.9%UTHR+5.4%EXEL-0.8%VCYT-4.0%HALO-3.1%RGEN-7.8%TGTX-3.9%QGEN-3.9%SRPT-3.6%PTGX-1.2%NBIX-0.8%VCEL-1.7%LEGN-2.9%INCY-3.5%ARDX-1.2%BMRN-2.6%PTCT-1.0%ANAB-3.2%BCRX-2.5%COLL+0.1%ACAD-1.3%

CELL SIZE IS PORTFOLIO WEIGHT · COLOR IS THE CHANGE IN THE LATEST AVAILABLE SNAPSHOT · TOP 40 POSITIONS

HoldingsDownload CSV
#HoldingWeightPriceDay52-wk
1NTRANATERA6.24%$408.47-1.2%
2ILMNILLUMINA6.13%$265.72-2.9%
3BIIBBIOGEN5.22%$222.82-1.4%
4GILDGILEAD SCIENCES5.16%$147.50-1.0%
5RPRXROYALTY PHARMA4.76%$57.63-1.3%
6AMGNAMGEN4.86%$407.27-3.4%
7VRTXVERTEX PHARMACEUTICALS4.83%$506.74-3.1%
8REGNREGENERON PHARMACEUTICALS4.57%$734.81-3.1%
9MRNAMODERNA3.54%$188.94-1.9%
10NVAXNOVAVAX3.17%$10.60-1.9%
11UTHRUNITED THERAPEUTICS2.57%$571.38+5.4%
12EXELEXELIXIS2.86%$57.94-0.8%
13VCYTVERACYTE2.89%$44.19-4.0%
14HALOHALOZYME THERAPEUTICS2.82%$106.94-3.1%
15RGENREPLIGEN2.96%$177.23-7.8%

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Sector weights
Healthcare100%
Health Technology91.43%
Health Services8.5%
Other0.1%
Mutual fund0.08%
PORTFOLIO COMPOSITION, LATEST DISCLOSURE
Country weights
United States100%
Ireland3.05%
Netherlands2.73%
Canada2.43%
PORTFOLIO COMPOSITION, LATEST DISCLOSURE
Performance
1 week-2.2%
1 month-1.9%
3 months+5.7%
6 months+23.7%
YTD+15.8%
1 year+32.8%
3 years—

PRICE RETURN, DISTRIBUTIONS NOT REINVESTED

Net flows
1 week—
1 month−$50M
3 months+$116M
YTD+$114M
1 year+$114M

CREATION/REDEMPTION DOLLARS, DAILY RECORDS

Monthly net flows
JulAugSepOctFebMarAprMayJunJulAugSep
DAILY CREATION/REDEMPTION RECORDS, TRAILING TWELVE MONTHS
The risk read
21%realized volatility, 30 days (annualized)
19%realized volatility, 1 year
-11.8%deepest fall from a peak, 1 year
-3.7%latest close versus that peak

The top holding is 6.2% of the book; the top ten carry 48%. Spread across 32+ names, it behaves like roughly 27 equally-weighted positions.

VOLATILITY & DRAWDOWN FROM THE DAILY TAPE · CONCENTRATION FROM THE LATEST DISCLOSED BOOK

Options tape
—calls · latest snapshot
—puts · latest snapshot
—put/call ratio
13Kshares traded
Most-traded holdings, options premiumBullishBearish
MRNA MODERNA$35M$34M
NTRA NATERA$3M$6M
AMGN AMGEN$3M$4M
UTHR UNITED THERAPEUTICS$2M$2M
QGEN QIAGEN NV$2M$2M

TODAY’S OPTIONS PREMIUM IN THE FUND’S UNDERLYING NAMES

The case against PBE

Due diligence cuts both ways. These funds sit on the same shelf and beat PBE on at least one dimension that matters — the fee, the asset base, or where the money is going.

FundFeeAssetsFlow, 1MThe case
SPDW State Street SPDR Portfolio Developed World ex-US ETF0.03%$41.5B+$286M-55bp on fee · 98× the assets · +$286M in over the monthHead-to-head
BBUS JPMorgan BetaBuilders U.S. Equity ETF0.02%$9.4B+$187M-56bp on fee · 22× the assets · +$187M in over the monthHead-to-head
SPMD State Street SPDR Portfolio S&P 400 Mid Cap ETF0.03%$18.2B+$199M-55bp on fee · 43× the assets · +$199M in over the monthHead-to-head
SPYG State Street SPDR Portfolio S&P 500 Growth ETF0.04%$56.2B+$717M-54bp on fee · 133× the assets · +$717M in over the monthHead-to-head
SPTM State Street SPDR Portfolio S&P 1500 Composite Stock Market ETF0.03%$14.1B+$235M-55bp on fee · 33× the assets · +$235M in over the monthHead-to-head
Sign in to save this to The RecordA timestamped copy for the file — documentation, not advice.
InstrumentsHarvest substitutesTrade cost at $1MClient tearsheetStress this fund
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